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Background: Dental Implant originally utilized for aesthetic and functional rehabilitation, this treatment option have transformed oral rehabilitation techniques and are now regarded as the gold standard of treatment for replacing single, partial, and full-arch teeth. With improvements in osteotomy technique, implant macro- and micro-geometry, surface treatment, types of implant prosthetic connections, and other aspects, the overall treatment duration has also been greatly shortened.Material & Methods:This study was carried out in two implant centers and is retrospective and descriptive. It was done in the Implant Surgery Centers of Banasree Dental and German Dental, Dhaka, Bangladesh. The research was carried out from January 2010 to June 2022. 63 people made up the entire sample for this study.Results:Most of the patients 21(33.3%) were aged between 51-60 years where most of the patients 36(57%) were female and 27(43%) were male. Maxilla was done in 45(71.4%) patients, mandible was done in 48(76.2%). 69(74.2%) implants were done on the anterior site and 24(25.8%) was done on posterior site. All the patients had a good primary stability of implant with an insertion torque of 30 N/cm or more. There were 100% survival rate after the implants and in good functional condition. All patients were happy with their implant.Conclusion:This approach of osteotomy preparation’s greater primary stability appears to have a minimal detrimental effect on implant success.
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Introduction: Reconstruction of head and neck cancerpatients is the most challenging areas in the human body.Patients and Methods: This study is a prospectiverandomized study of 50 consecutive operated patients for headand neck cancer reconstructive surgeries including pedicledand free flaps (radial forearm and fibula free flaps). All patientswere thoroughly monitored postoperatively for its morbidity andsurgical outcome.Results: Although complications are inevitable in a percentageof patients, it is good postoperative care and monitoring thatdetermines the success or failure of the reconstruction andalso permits early salvage of a failing flap.Conclusion: Teamwork and cooperation among members ofthe reconstructive team are critical. We reviewed significanceof clinical care and monitoring of reconstructed head and neckpatients in the intraoperative and postoperative periods.
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Vitamin C, also known as L-ascorbic acid, is an essential vitamin with pleiotropic functions, ranging from antioxidant to anti-microbial functions. Evidence suggests that vitamin C acts against inflammation, oxidative stress, autophagy chaos, and immune dysfunction. The ability to activate and enhance the immune system makes this versatile vitamin a prospective therapeutic agent amid the current situation of coronavirus disease 2019 (COVID-19). Being highly effective against the influenza virus, causing the common cold, vitamin C may also function against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its associated complications. Severe infections need higher doses of the vitamin to compensate for the augmented inflammatory response and metabolic demand that commonly occur during COVID-19. Compelling evidence also suggests that a high dose of vitamin C (1.5 g/kg body weight) in inflammatory conditions can result in effective clinical outcomes and thus can be employed to combat COVID-19. However, further studies are crucial to delineate the mechanism underlying the action of vitamin C against COVID-19. The current review aims to reposition vitamin C as an alternative approach for alleviating COVID-19-associated complications.
ABSTRACT
Vitamin C, also known as L-ascorbic acid, is an essential vitamin with pleiotropic functions, ranging from antioxidant to anti-microbial functions. Evidence suggests that vitamin C acts against inflammation, oxidative stress, autophagy chaos, and immune dysfunction. The ability to activate and enhance the immune system makes this versatile vitamin a prospective therapeutic agent amid the current situation of coronavirus disease 2019 (COVID-19). Being highly effective against the influenza virus, causing the common cold, vitamin C may also function against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its associated complications. Severe infections need higher doses of the vitamin to compensate for the augmented inflammatory response and metabolic demand that commonly occur during COVID-19. Compelling evidence also suggests that a high dose of vitamin C (1.5 g/kg body weight) in inflammatory conditions can result in effective clinical outcomes and thus can be employed to combat COVID-19. However, further studies are crucial to delineate the mechanism underlying the action of vitamin C against COVID-19. The current review aims to reposition vitamin C as an alternative approach for alleviating COVID-19-associated complications.
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Objective: To analyze the phytochemical constituents responsible for the plausible antioxidant effect of methanolic extract of the seed, pulp and peel of Baccaurea ramiflora Lour. Methods: Fresh seed, pulp, and peel of Baccaurea ramiflora fruits were extracted with methanol (MEBRse, MEBRpu, MEBRpe) and evaluated by phytochemical analysis for their content of innumerable metabolites (primary and secondary) viz. carbohydrates, alkaloids, glycosides, tannins, phenols, terpenoids, flavonoids, proteins, and fixed oils. The antioxidant efficacy was assessed through different assay methods viz. 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, total antioxidant capacity (TAC) and reducing power capacity (RPC). Estimation of total phenolic content (TPC), and total flavonoid content (TFC) was also done to confirm the presence of these phytochemicals. Results: It was revealed from the phytochemical analysis of MEBRse that alkaloids, glycosides, carbohydrates, phenols, and flavonoids were present, while that of MEBRpu showed the existence of carbohydrates, proteins, alkaloids, glycosides, phenols, saponins, flavonoids, and fixed oils. Presence of carbohydrates, alkaloids, phenols, tannins, flavonoids, and terpenoids were found in the MEBRpe. A significant antioxidant activity was revealed by the MEBRpu [EC
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Objective:To analyze the phytochemical constituents responsible for the plausible antioxidant effect of methanolic extract of the seed, pulp and peel of Baccaurea ramiflora Lour.Methods:Fresh seed, pulp, and peel of Baccaurea ramiflora fruits were extracted with methanol (MEBRse, MEBRpu, MEBRpe) and evaluated by phytochemical analysis for their content of innumerable metabolites (primary and secondary) viz. carbohydrates, alkaloids, glycosides, tannins, phenols, terpenoids, flavonoids, proteins, and fixed oils. The antioxidant efficacy was assessed through different assay methods viz. 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging activity, total antioxidant capacity (TAC) and reducing power capacity (RPC). Estimation of total phenolic content (TPC), and total flavonoid content (TFC) was also done to confirm the presence of these phytochemicals.Results:It was revealed from the phytochemical analysis of MEBRse that alkaloids, glycosides, carbohydrates, phenols, and flavonoids were present, while that of MEBRpu showed the existence of carbohydrates, proteins, alkaloids, glycosides, phenols, saponins, flavonoids, and fixed oils. Presence of carbohydrates, alkaloids, phenols, tannins, flavonoids, and terpenoids were found in the MEBRpe. A significant antioxidant activity was revealed by the MEBRpu [ECConclusions:This study suggests that MEBRpu has a significantly higher antioxidant property than MEBRpe and MEBRse. These extracts might be advantageous in prevention or decelerating the progress of different diseases related to oxidative-stress/damage. Moreover, detailed analysis of these extracts is required to identify the presence of promising compound(s) responsible for their antioxidant activity.
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Objective: To evaluate the toxic effect of hydrose used in the molasses preparation in Bangladesh. Methods: Molasses were collected from open markets in different parts of Bangladesh. The presence of hydrose in selected molasses was detected using commercial kit. To evaluate the toxic effect of hydrose, Swiss albino male mice were divided into four groups. Group I was used as control, while Groups II, III and IV received hydrose mixing food (5, 10 and 25 g/ kg food), respectively, and these supplementations were continued to the end of the study (16 weeks). Blood was collected from thoracic arteries of the mice under ether anesthesia and then organs were taken. To determine the effect of hydrose on host, blood indices related to liver, heart and kidney dysfunctions were measured. Result: Creatinine and urea levels were significantly (P < 0.05) increased in a dose dependent manner in hydrose treated mice, whereas calcium level was significantly decreased in hydrose exposed mice compared to control mice. Histological study of kidney showed the glomeruler inflammation, increased diameter of renal glomeruli and enlargement of proximal tubular lumen of kidneys of mice exposed to hydrose compared to that of control animals. Conclusion: The results of this study indicated that use of hydrose in molasses and other food preparations in Bangladesh may cause kidney impairment.
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Clinical presentations of kala-azar [visceral leishmaniasis] are varied in children and adults. This may at Least initially mimic many tropical and hepatobilliary diseases. This paper is an attempt to see the clinical presentations of kala-azar in children. Eleven cases are analyzed, retrospectively admitted in a pediatric unit of a tertiary care hospital in the southern part of Bangladesh. Fever 91%, Jaundice 55%, splenomegaly 100%, hepatomegaly 91% are common findings. Presence of jaundice and ascites may mimic chronic liver disease which is suspected in 36% in this series. Awareness regarding these uncommon features will help in diagnosis
Subject(s)
Humans , Male , Female , Child , Retrospective Studies , Fever/etiology , Jaundice/etiology , Splenomegaly/etiology , Hepatomegaly/etiology , Ascites/etiology , Leishmaniasis, Visceral/diagnosisABSTRACT
An 18 years olds girl, presented with complaints of continued low grade fever, jet black skin rash and photosensitivity, generalized hyperpigmentation, marked anorexia with extreme lethargy, dull aching abdominal pain with frequent loose stools. Painless oral ulcers, moderate loss of hair, remarkable weight loss, with joint pain, morning stiffing, colour changes of fingers on exposure to cold with digital ulceration. She was amenorrhoic during the period of illness. She was extremely ill with moderate anaemia, raised temperature, postural hypotension, pigmented butterfly rashes on the face and discoid lesions all over the body. Marked pigmentation on the palmer creases, base of the nails, knuckles of the hands, buccal mucosa, gums, tongue, aerola of breasts and valvae, with oral ulcers were present. There were symmetrical polyarthritis with restriction of movement. Laboratory investigations showed an elevated ESR, low haemoglobin, normal platelets, total and differential count of WBC, prothrombin time and APTT were normal, with positive ANA and anti-ds DNA antibody, normal IgG anticardiolipin antibody and a positive direct Coombs' test, with moderate proteinuria. X-ray chest and KUB regions were normal. Abdominal CT scan showed bilateral adrenal cortical atrophy. Tuberculin test was negative. There was hyponatraemia and relative hyperkalaemia. Low serum cortisol level at 8:00 am and positive short synecthine test. Treatment started with prednisolone 1mg/kg in three divided doses which resulted in dramatic improvement, then prednisolone was gradually tappered to 7.5 mg daily. She was in remission during four years follow-up
Subject(s)
Humans , Female , Addison Disease/diagnosisABSTRACT
A total of 370 patients [male 242 and female 128] of dengue syndrome admitted in the medical units of Khulna medical college hospital from July to Dec. 2000 were studied. Age of the patients ranged from 2-70 yrs. Highest number of patients 230[62.16%] were from 1[st] to 3[rd] decade. Students [194], Housewives [55], businessmen [43] and preschool children [36] were the commonly affected group. Fever was the commonest presentation [100%], other symptoms were headache in 115 [31.08%], rash in 105 [28.37%], bodyache in 98 [26.48%], abdominal pain in 66 [17.83%], vomiting in 88 [23.78%] and retroorbital pain in 45 [12.16%] cases. Among the bleeding manifestations, commonest was haematemesis and melaena in 206 [55.67%] cases, gum bleeding in 61 [16.48%], conjunctival haemorrhage in 40 [10.81%]. Haematocrit was high and platelet count was low in majority of the cases. The patients were diagnosed as Dengue Fever [DF] 169 [45.67 %], Dengue haemorrhage fever [DHF] 185 [50%], and Dengue shock syndrome [DSS] 16 [43.2% cases. Out of 370 patients treated 350 [94.59%] recovered completely; 15 [4.05%] expired due to DHF and DSS